Stain normalization in digital pathology: Clinical multi-center evaluation of image quality

• Main Authors: Nicola Michielli (Author), Alessandro Caputo (Author), Manuela Scotto (Author), Alessandro Mogetta (Author), Orazio Antonino Maria Pennisi (Author), Filippo Molinari (Author), Davide Balmativola (Author), Martino Bosco (Author), Alessandro Gambella (Author), Jasna Metovic (Author), Daniele Tota (Author), Laura Carpenito (Author), Paolo Gasparri (Author), Massimo Salvi (Author)
• Format: Book
• Published: Elsevier, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In digital pathology, the final appearance of digitized images is affected by several factors, resulting in stain color and intensity variation. Stain normalization is an innovative solution to overcome stain variability. However, the validation of color normalization tools has been assessed only fr...