Effects of Sodium and Amino Acid Substrate Availability upon the Expression and Stability of the SNAT2 (SLC38A2) Amino Acid Transporter

• Main Authors: Thorsten M. Hoffmann (Author), Emma Cwiklinski (Author), Dinesh S. Shah (Author), Clare Stretton (Author), Russell Hyde (Author), Peter M. Taylor (Author), Harinder S. Hundal (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The SNAT2 (SLC38A2) System A amino acid transporter mediates Na+-coupled cellular uptake of small neutral α-amino acids (AAs) and is extensively regulated in response to humoral and nutritional cues. Understanding the basis of such regulation is important given that AA uptake via SNAT2 has been link...