Salmonella Typhi whole genome sequencing in Rwanda shows a diverse historical population with recent introduction of haplotype H58.

• Main Authors: Jean Pierre Rutanga (Author), Tessa de Block (Author), Wim L Cuypers (Author), Josephine Cafmeyer (Author), Marjan Peeters (Author), Esperance Umumararungu (Author), Jean Claude S Ngabonziza (Author), Aniceth Rucogoza (Author), Olivier Vandenberg (Author), Delphine Martiny (Author), Angélique Dusabe (Author), Théoneste Nkubana (Author), Gordon Dougan (Author), Claude Mambo Muvunyi (Author), Ivan Emil Mwikarago (Author), Jan Jacobs (Author), Stijn Deborggraeve (Author), Sandra Van Puyvelde (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Salmonella enterica serovar Typhi (S. Typhi) is the cause of typhoid fever, presenting high rates of morbidity and mortality in low- and middle-income countries. The H58 haplotype shows high levels of antimicrobial resistance (AMR) and is the dominant S. Typhi haplotype in endemic areas of Asia and...