Evidence‐based insomnia treatment strategy using novel orexin antagonists: A review

• Main Authors: Taro Kishi (Author), Maika Nishida (Author), Michinori Koebis (Author), Takehiro Taninaga (Author), Kenzo Muramoto (Author), Naoki Kubota (Author), Margaret Moline (Author), Kenji Sakuma (Author), Makoto Okuya (Author), Ikuo Nomura (Author), Nakao Iwata (Author)
• Format: Book
• Published: Wiley, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Most conventional insomnia medications are gamma‐aminobutylic acid receptor agonists. However, physical dependence is a concern and one of the major limiting factors for long‐term treatment. The dual orexin receptor antagonists, suvorexant and lemborexant, were recently approved for treatin...