Nanoparticle-Based RNAi Therapeutics Targeting Cancer Stem Cells: Update and Prospective

• Main Authors: Yongquan Tang (Author), Yan Chen (Author), Zhe Zhang (Author), Bo Tang (Author), Zongguang Zhou (Author), Haining Chen (Author)
• Format: Bog
• Udgivet: MDPI AG, 2021-12-01T00:00:00Z.
• Fag: article
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Cancer stem cells (CSCs) are characterized by intrinsic self-renewal and tumorigenic properties, and play important roles in tumor initiation, progression, and resistance to diverse forms of anticancer therapy. Accordingly, targeting signaling pathways that are critical for CSC maintenance and biofu...