Nasal double DNA adjuvant induces salivary FimA-specific secretory IgA antibodies in young and aging mice and blocks Porphyromonas gingivalis binding to a salivary protein

Abstract Background We previously showed that nasal administration of a combination of dendritic cell (DC) targeted DNA plasmid expressing Flt3 ligand and CpG oligodeoxynucleotides 1826 as a mucosal adjuvant (double adjuvant, DA) provoked protective immunity in the upper respiratory tract of young a...

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Bibliographic Details
Main Authors: Kenjiro Kobuchi (Author), Kosuke Kataoka (Author), Yoichiro Taguchi (Author), Tatsuro Miyake (Author), Makoto Umeda (Author)
Format: Book
Published: BMC, 2019-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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