Long-Term Arthralgia after Mayaro Virus Infection Correlates with Sustained Pro-inflammatory Cytokine Response.

• Main Authors: Felix W Santiago (Author), Eric S Halsey (Author), Crystyan Siles (Author), Stalin Vilcarromero (Author), Carolina Guevara (Author), Jesus A Silvas (Author), Cesar Ramal (Author), Julia S Ampuero (Author), Patricia V Aguilar (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mayaro virus (MAYV), an alphavirus similar to chikungunya virus (CHIKV), causes an acute debilitating disease which results in the development of long-term arthralgia in more than 50% of infected individuals. Currently, the immune response and its role in the development of MAYV-induced persistent a...