Targeting M2 Macrophages with a Novel NADPH Oxidase Inhibitor

• Main Authors: Sébastien Dilly (Author), Miguel Romero (Author), Stéphanie Solier (Author), Olivier Feron (Author), Chantal Dessy (Author), Anny Slama Schwok (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ROS in cancer cells play a key role in pathways regulating cell death, stemness maintenance, and metabolic reprogramming, all of which have been implicated in resistance to chemo/ immunotherapy. Adjusting ROS levels to reverse the resistance of cancer cells without impairing normal cell functions is...