Development and Validation of Liquid Chromatography-Tandem Mass Spectrometry Method for Simple Analysis of Sumatriptan and its Application in Bioequivalence Study

• Main Authors: Wisut Wichitnithad (Author), Siriwan Nantaphol (Author), Petploy Vicheantawatchai (Author), Thanyaporn Kiatkumjorn (Author), Wachirasak Wangkangwan (Author), Pornchai Rojsitthisak (Author)
• Format: Book
• Published: MDPI AG, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This work demonstrated a sensitive, selective, and simple liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for quantitation of sumatriptan in human plasma samples. Terazosin was used as an internal standard to minimize the variability during sample processing and detection. Sample cl...