Exposure‐Safety Analyses Identify Predictors of Change in Bone Mineral Density and Support Elagolix Labeling for Endometriosis‐Associated Pain

• Main Authors: Ahmed Abbas Suleiman (Author), Ahmed Nader (Author), Insa Winzenborg (Author), Denise Beck (Author), Akshanth R. Polepally (Author), Juki Ng (Author), Peter Noertersheuser (Author), Nael M. Mostafa (Author)
• Format: Book
• Published: Wiley, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Elagolix is a novel oral gonadotropin releasing hormone receptor antagonist, that can suppress estradiol in a dose‐dependent manner. It is indicated for management of moderate‐to‐severe pain associated with endometriosis. A population exposure‐response model describing the relationship between elago...