Piezo 1 is involved in intraocular pressure regulation

• Main Authors: Wataru Morozumi (Author), Kota Aoshima (Author), Satoshi Inagaki (Author), Yuki Iwata (Author), Shinsuke Nakamura (Author), Hideaki Hara (Author), Masamitsu Shimazawa (Author)
• Format: Book
• Published: Elsevier, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Trabecular meshwork (TM) regulates the intraocular pressure (IOP) through the control of aqueous humor outflow. Previous reports show that TM cells express 11 types of mechanosensitive molecules, including Piezo 1, which sense mechanical stimuli. However, the role of Piezo 1 on TM remains unclear. T...