Enhanced healing efficacy of an optimized gabapentin-melittin nanoconjugate gel-loaded formulation in excised wounds of diabetic rats

• Main Authors: Hani Z. Asfour (Author), Nabil A. Alhakamy (Author), Osama A. A. Ahmed (Author), Usama A. Fahmy (Author), Shadab Md (Author), Mohamed A. El-Moselhy (Author), Waleed Y. Rizg (Author), Adel F. Alghaith (Author), Basma G. Eid (Author), Ashraf B. Abdel-Naim (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present study aimed to design and optimize, a nanoconjugate of gabapentin (GPN)-melittin (MLT) and to evaluate its healing activity in rat diabetic wounds. To explore the wound healing potency of GPN-MLT nanoconjugate, an in vivo study was carried out. Diabetic rats were subjected to excision wo...