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Impact of global PTP1B deficiency on the gut barrier permeability during NASH in mice

Objective: Non-alcoholic steatohepatitis (NASH) is characterized by a robust pro-inflammatory component at both hepatic and systemic levels together with a disease-specific gut microbiome signature. Protein tyrosine phosphatase 1 B (PTP1B) plays distinct roles in non-immune and immune cells, in the...

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Main Authors: Carmen Rubio (Author), Marta Puerto (Author), Juan J. García-Rodríquez (Author), Van B. Lu (Author), Irma García-Martínez (Author), Rosa Alén (Author), Patricia Sanmartín-Salinas (Author), M. Val Toledo-Lobo (Author), Jorge Saiz (Author), Javier Ruperez (Author), Coral Barbas (Author), Luis Menchén (Author), Fiona M. Gribble (Author), Frank Reimann (Author), Luis G. Guijarro (Author), Jose M. Carrascosa (Author), Ángela M. Valverde (Author)
Format: Book
Published: Elsevier, 2020-05-01T00:00:00Z.
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