ICG-001, an Inhibitor of the β-Catenin and cAMP Response Element-Binding Protein Dependent Gene Transcription, Decreases Proliferation but Enhances Migration of Osteosarcoma Cells

• Үндсэн зохиолчид: Geoffroy Danieau (Зохиогч), Sarah Morice (Зохиогч), Sarah Renault (Зохиогч), Régis Brion (Зохиогч), Kevin Biteau (Зохиогч), Jérôme Amiaud (Зохиогч), Marie Cadé (Зохиогч), Dominique Heymann (Зохиогч), Frédéric Lézot (Зохиогч), Franck Verrecchia (Зохиогч), Françoise Rédini (Зохиогч), Bénédicte Brounais-Le Royer (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2021-05-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

High-grade osteosarcomas are the most frequent malignant bone tumors in the pediatric population, with 150 patients diagnosed every year in France. Osteosarcomas are associated with low survival rates for high risk patients (metastatic and relapsed diseases). Knowing that the canonical Wnt signaling...