Combination of G-CSF and AMD3100 Improves the Anti-inflammatory Effect of Mesenchymal Stem Cells on Inducing M2 Polarization of Macrophages Through NF-κB-IL1RA Signaling Pathway

• Main Authors: Long Chen (Author), Qian Zhang (Author), Qin-Hua Chen (Author), Feng-Yin Ran (Author), Li-Mei Yu (Author), Xiu Liu (Author), Qiang Fu (Author), Gong-Yu Song (Author), Jun-Ming Tang (Author), Tao Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mobilized peripheral blood-derived mesenchymal stem cells (PB-MSCs) mainly derived from bone marrow-derived MSCs (BM-MSCs) exert a similar anti-inflammatory effect. However, the mechanism of anti-inflammatory effect of mobilized PB-MSCs by a combination of G-CSF and AMD3100 remains unclear. Cultured...