Mycobacterial Hsp65 antigen upregulates the cellular immune response of healthy individuals compared with tuberculosis patients

• Main Authors: Pryscilla Fanini Wowk (Author), Luís Henrique Franco (Author), Denise Morais da Fonseca (Author), Marina Oliveira Paula (Author), Élcio dos Santos Oliveira Vianna (Author), Ana Paula Wendling (Author), Valéria Maria Augusto (Author), Silvana Maria Elói-Santos (Author), Andréa Teixeira-Carvalho (Author), Flávia Dias Coelho Silva (Author), Solange Alves Vinhas (Author), Olindo Assis Martins-Filho (Author), Moisés Palaci (Author), Célio Lopes Silva (Author), Vânia Luiza Deperon Bonato (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Previously we showed that 65-kDa Mycobacterium leprae heat shock protein (Hsp65) is a target for the development of a tuberculosis vaccine. Here we evaluated peripheral blood mononuclear cells (PBMC) from healthy individuals or tuberculosis patients stimulated with two forms of Hsp65 antigen, recomb...