Enabling In Vivo Optical Imaging of an Osmium Photosensitizer by Micellar Formulation

• Main Authors: Drashti Shah (Author), Menitte Eroy (Author), John Fakhry (Author), Azophi Moffat (Author), Kevin Fritz (Author), Houston D. Cole (Author), Colin G. Cameron (Author), Sherri A. McFarland (Author), Girgis Obaid (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osmium (Os)-based photosensitizers (PSs) exhibit unique broad, red-shifted absorption, favoring PDT activity at greater tissue depths. We recently reported on a potent Os(II) PS, <i>rac-</i>[Os(phen)₂(IP-4T)](Cl)₂ (ML18J03) with submicromolar...