Sustainable Synthesis of <i>p</i>-Hydroxycinnamic Diacids through Proline-Mediated Knoevenagel Condensation in Ethanol: An Access to Potent Phenolic UV Filters and Radical Scavengers

• Главные авторы: Benjamin Rioux (Автор), Cédric Peyrot (Автор), Matthieu M. Mention (Автор), Fanny Brunissen (Автор), Florent Allais (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2020-04-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

<i>p</i>-Hydroxycinnamic diacids are reaction intermediates of the classical Knoevenagel-Doebner condensation between malonic acid and benzaldehydes. As they are generally obtained in low yields, they remain relatively under-studied and under-exploited. Herein, we developed and optimized...