The miR-200-Zeb1 axis regulates key aspects of β-cell function and survival in vivo

• Príomhchruthaitheoirí: Alexandra C. Title (Údar), Pamuditha N. Silva (Údar), Svenja Godbersen (Údar), Lynn Hasenöhrl (Údar), Markus Stoffel (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Elsevier, 2021-11-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Objective: The miR-200-Zeb1 axis regulates the epithelial-to-mesenchymal transition (EMT), differentiation, and resistance to apoptosis. A better understanding of these processes in diabetes is highly relevant, as β-cell dedifferentiation and apoptosis contribute to the loss of functional β-cell mas...