Effect of Microencapsulation Shear Stress on the Structural Integrity and Biological Activity of a Model Monoclonal Antibody, Trastuzumab
The aim of the present study was to investigate the influence of process shear stressors on the stability of a model monoclonal antibody, trastuzumab. Trastuzumab, at concentrations of 0.4-4.0 mg/mL, was subjected to sonication, freeze-thaw, lyophilisation, spray drying and was encapsulated into mic...
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| Main Authors: | , , , |
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| Formato: | Livro |
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MDPI AG,
2011-08-01T00:00:00Z.
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| Cód. Barras: 1 | Disponível |