Effect of Microencapsulation Shear Stress on the Structural Integrity and Biological Activity of a Model Monoclonal Antibody, Trastuzumab

The aim of the present study was to investigate the influence of process shear stressors on the stability of a model monoclonal antibody, trastuzumab. Trastuzumab, at concentrations of 0.4-4.0 mg/mL, was subjected to sonication, freeze-thaw, lyophilisation, spray drying and was encapsulated into mic...

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Main Authors: Ritesh M. Pabari (Author), Benedict Ryan (Author), Catherine McCarthy (Author), Zebunnissa Ramtoola (Author)
Format: Book
Published: MDPI AG, 2011-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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