The genetic and molecular basis of O-antigenic diversity in Burkholderia pseudomallei lipopolysaccharide.

• Main Authors: Apichai Tuanyok (Author), Joshua K Stone (Author), Mark Mayo (Author), Mirjam Kaestli (Author), Jeffrey Gruendike (Author), Shalamar Georgia (Author), Stephanie Warrington (Author), Travis Mullins (Author), Christopher J Allender (Author), David M Wagner (Author), Narisara Chantratita (Author), Sharon J Peacock (Author), Bart J Currie (Author), Paul Keim (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lipopolysaccharide (LPS) is one of the most important virulence and antigenic components of Burkholderia pseudomallei, the causative agent of melioidosis. LPS diversity in B. pseudomallei has been described as typical, atypical or rough, based upon banding patterns on SDS-PAGE. Here, we studied the...