Case report: Accelerated regression of giant cardiac rhabdomyomas in neonates with low dose everolimus

• Main Authors: Daniel Hurtado-Sierra (Author), Judy Ximena Ramos Garzón (Author), Lyda Z. Rojas (Author), Oscar Fernández-Gómez (Author), Francisco Manrique-Rincón (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cardiac rhabdomyoma (CRHM) is the principal cardiac tumor in children and is most often associated with tuberous sclerosis complex (TSC). Mutations in the TSC1 and TSC2 genes cause the overactivation of the mammalian Target of Rapamycin (mTOR). This protein family is responsible for abnormal cell pr...