Endothelin receptor antagonists: effects on extracellular matrix synthesis in primary cultures of skin fibroblasts from systemic sclerosis patients
Endothelin-1 (ET-1) seems to enhance the pro-fibrotic protein synthesis by skin fibroblasts and its effects are mediated by endothelin-A and B (ETA and ETB) receptors. This study aimed to investigate the effects of ETA and ETB receptor antagonists (ETARA-sitaxentan and ETA/BRA-bosentan) on type I co...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
| Published: |
PAGEPress Publications,
2012-12-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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