Fabrication of a drug delivery system that enhances antifungal drug corneal penetration

• Main Authors: Jingguo Li (Author), Zhanrong Li (Author), Zhen Liang (Author), Lei Han (Author), Huayang Feng (Author), Siyu He (Author), Junjie Zhang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fungal keratitis (FK) remains a severe eye disease, and effective therapies are limited by drug shortages and critical ocular barriers. Despite the high antifungal potency and broad spectrum of econazole, its strong irritant and insolubility in water hinder its ocular application. We designed and fa...