Cytokine RNA In Situ Hybridization Permits Individualized Molecular Phenotyping in Biopsies of Psoriasis and Atopic Dermatitis

• Main Authors: Alice Wang (Author), Alexander L. Fogel (Author), Michael J. Murphy (Author), Gauri Panse (Author), Meaghan K. McGeary (Author), Jennifer M. McNiff (Author), Marcus Bosenberg (Author), Matthew D. Vesely (Author), Jeffrey M. Cohen (Author), Christine J. Ko (Author), Brett A. King (Author), William Damsky (Author)
• Format: Book
• Published: Elsevier, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Detection of individual cytokines in routine biopsies from patients with inflammatory skin diseases has the potential to personalize diagnosis and treatment selection, but this approach has been limited by technical feasibility. We evaluate whether a chromogen-based RNA in situ hybridization approac...