First report of a successful pregnancy by preimplantation genetic testing for Beckwith-Wiedemann syndrome

• Main Authors: Ih-Jane Yang (Author), Yi-An Tu (Author), Song-Po Pan (Author), Ting-Chi Huang (Author), Chih-Ling Chen (Author), Ming-Wei Lin (Author), Yi-Yi Tsai (Author), Yi-Lin Yao (Author), Yi-Ning Su (Author), Shee-Uan Chen (Author)
• Format: Book
• Published: Elsevier, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Beckwith-Wiedemann syndrome (BWS) is a rare imprinting gene disorder. Maternal CDKN1C mutation comprises 5% of etiologies of BWS. There is no successful report of preventing BWS by preimplantation genetic testing for monogenic disease (PGT-M) in the literature. Is PGT-M applicable for pre...