Discovery of Leptospira spp. seroreactive peptides using ORFeome phage display.

• Main Authors: Siti Roszilawati Ramli (Author), Gustavo M S G Moreira (Author), Jonas Zantow (Author), Marga G A Goris (Author), Van Kinh Nguyen (Author), Natalia Novoselova (Author), Frank Pessler (Author), Michael Hust (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Leptospirosis is the most common zoonotic disease worldwide. The diagnostic performance of a serological test for human leptospirosis is mainly influenced by the antigen used in the test assay. An ideal serological test should cover all serovars of pathogenic leptospires with high sensiti...