Development and validation of stability indicating RP-HPLC method for the simultaneous estimation of Sofosbuvir and Ledipasvir in bulk and their combined dosage form

• Main Authors: S.K. Mastanamma (Author), S.K. Chandini (Author), S.K. Reehana (Author), P. Saidulu (Author)
• Formato: Libro
• Publicado: SpringerOpen, 2018-12-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Objective: A simple, specific, accurate and economic reverse phase liquid chromatographic method was developed for the simultaneous estimation of Sofosbuvir and Ledipasvir in bulk and tablet dosage form. Method: The method has shown adequate separation of Sofosbuvir and Ledipasvir from their degrada...