NLRP3 inflammasome inhibitor MCC950 attenuates primary dysmenorrhea in mice via the NF-κB/COX-2/PG pathway

• Main Authors: Biao Tang (Author), Dan Liu (Author), Lingyu Chen (Author), Yu Liu (Author)
• 格式: 图书
• 出版: BMC, 2020-06-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Abstract Background Primary dysmenorrhea (PD) constitutes a common gynecological disease among young women. The NLRP3 inflammasome may be activated and expressed in PD, but the mechanistic link between NLRP3 inflammasome activation and PD is still unclear. Methods To investigate the potential role o...