A stochastic mixed effects model to assess treatment effects and fluctuations in home‐measured peak expiratory flow and the association with exacerbation risk in asthma

Abstract Home‐based measures of lung function, inflammation, symptoms, and medication use are frequently collected in respiratory clinical trials. However, new statistical approaches are needed to make better use of the information contained in these data‐rich variables. In this work, we use data fr...

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Main Authors: Jacob Leander (Author), Mats Jirstrand (Author), Ulf G. Eriksson (Author), Robert Palmér (Author)
Format: Book
Published: Wiley, 2022-02-01T00:00:00Z.
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