Dihydroartemisinin Inhibits the Proliferation of Esophageal Squamous Cell Carcinoma Partially by Targeting AKT1 and p70S6K

• Main Authors: Lili Zhu (Author), Xinhuan Chen (Author), Yanyan Zhu (Author), Jiace Qin (Author), Tingting Niu (Author), Yongwei Ding (Author), Yang Xiao (Author), Yanan Jiang (Author), Kangdong Liu (Author), Jing Lu (Author), Wanjing Yang (Author), Yan Qiao (Author), Ge Jin (Author), Junfen Ma (Author), Ziming Dong (Author), Jimin Zhao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dihydroartemisinin (DHA), a sesquiterpene lactone with endoperoxide bridge, is one of the derivatives of artemisinin. In addition to having good antimalarial properties, DHA exhibits anticancer effects including against malignant solid tumors. However, the mechanism by which DHA inhibits the progres...