Limited Impact of the Protein Corona on the Cellular Uptake of PEGylated Zein Micelles by Melanoma Cancer Cells

• Main Authors: Jitkasem Meewan (Author), Sukrut Somani (Author), Partha Laskar (Author), Craig Irving (Author), Margaret Mullin (Author), Stuart Woods (Author), Craig W. Roberts (Author), Abdullah R. Alzahrani (Author), Valerie A. Ferro (Author), Suzanne McGill (Author), Stefan Weidt (Author), Richard Burchmore (Author), Christine Dufès (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The formation of a protein layer "corona" on the nanoparticle surface upon entry into a biological environment was shown to strongly influence the interactions with cells, especially affecting the uptake of nanomedicines. In this work, we present the impact of the protein corona on the upt...