SPE-UPLC-MS/MS assay for determination of letrozole in human plasma and its application to bioequivalence study in healthy postmenopausal Indian women

• Главные авторы: Pravin G. Vanol (Автор), Puran Singhal (Автор), Priyanka A. Shah (Автор), Jaivik V. Shah (Автор), Pranav S. Shrivastav (Автор), Mallika Sanyal (Автор)
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• Опубликовано: Elsevier, 2016-08-01T00:00:00Z.
• Предметы: article
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A rapid and sensitive ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method is described for determination of letrozole in human plasma. Following solid phase extraction (SPE) of letrozole and letrozole-d4 on Orochem DVB-LP cartridges, chromatography was performed on A...