Diverging targets mediate the pathological roleof miR-199a-5p and miR-199a-3p by promoting cardiac hypertrophy and fibrosis

• Main Authors: Ni Zeng (Author), Yu-Qing Huang (Author), Yu-Min Yan (Author), Zhi-Qin Hu (Author), Zhuo Zhang (Author), Jia-Xin Feng (Author), Ji-Shen Guo (Author), Jie-Ning Zhu (Author), Yong-Heng Fu (Author), Xi-Pei Wang (Author), Meng-Zhen Zhang (Author), Jin-Zhu Duan (Author), Xi-Long Zheng (Author), Jin-Dong Xu (Author), Zhi-Xin Shan (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

MicroRNA-199a-5p (miR-199a-5p) and -3p are enriched in the myocardium, but it is unknown whether miR-199a-5p and -3p are co-expressed in cardiac remodeling and what roles they have in cardiac hypertrophy and fibrosis. We show that miR-199a-5p and -3p are co-upregulated in the mouse and human myocard...