Diverging targets mediate the pathological roleof miR-199a-5p and miR-199a-3p by promoting cardiac hypertrophy and fibrosis

• Egile Nagusiak: Ni Zeng (Egilea), Yu-Qing Huang (Egilea), Yu-Min Yan (Egilea), Zhi-Qin Hu (Egilea), Zhuo Zhang (Egilea), Jia-Xin Feng (Egilea), Ji-Shen Guo (Egilea), Jie-Ning Zhu (Egilea), Yong-Heng Fu (Egilea), Xi-Pei Wang (Egilea), Meng-Zhen Zhang (Egilea), Jin-Zhu Duan (Egilea), Xi-Long Zheng (Egilea), Jin-Dong Xu (Egilea), Zhi-Xin Shan (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2021-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

MicroRNA-199a-5p (miR-199a-5p) and -3p are enriched in the myocardium, but it is unknown whether miR-199a-5p and -3p are co-expressed in cardiac remodeling and what roles they have in cardiac hypertrophy and fibrosis. We show that miR-199a-5p and -3p are co-upregulated in the mouse and human myocard...