Alterations in peripheral blood B cell subsets and dynamics of B cell responses during human schistosomiasis.

• Main Authors: Lucja A Labuda (Author), Ulysse Ateba-Ngoa (Author), Eliane Ngoune Feugap (Author), Jorn J Heeringa (Author), Luciën E P M van der Vlugt (Author), Regina B A Pires (Author), Ludovic Mewono (Author), Peter G Kremsner (Author), Menno C van Zelm (Author), Ayola A Adegnika (Author), Maria Yazdanbakhsh (Author), Hermelijn H Smits (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Antibody responses are thought to play an important role in control of Schistosoma infections, yet little is known about the phenotype and function of B cells in human schistosomiasis. We set out to characterize B cell subsets and B cell responses to B cell receptor and Toll-like receptor 9 stimulat...