Reducing neonatal Fc receptor binding enhances clearance and brain-to-blood ratio of TfR-delivered bispecific amyloid-β antibody

ABSTRACTRecent development of amyloid-β (Aβ)-targeted immunotherapies for Alzheimer's disease (AD) have highlighted the need for accurate diagnostic methods. Antibody-based positron emission tomography (PET) ligands are well suited for this purpose as they can be directed toward the same target...

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Main Authors: Eva Schlein (Author), Ken G. Andersson (Author), Tiffany Dallas (Author), Stina Syvänen (Author), Dag Sehlin (Author)
Format: Book
Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
Copy 1 Available