Reducing neonatal Fc receptor binding enhances clearance and brain-to-blood ratio of TfR-delivered bispecific amyloid-β antibody
ABSTRACTRecent development of amyloid-β (Aβ)-targeted immunotherapies for Alzheimer's disease (AD) have highlighted the need for accurate diagnostic methods. Antibody-based positron emission tomography (PET) ligands are well suited for this purpose as they can be directed toward the same target...
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Main Authors: | Eva Schlein (Author), Ken G. Andersson (Author), Tiffany Dallas (Author), Stina Syvänen (Author), Dag Sehlin (Author) |
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Format: | Book |
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Taylor & Francis Group,
2024-12-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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