Harnessing the cyclization strategy for new drug discovery

• Hoofdauteurs: Kai Tang (Auteur), Shu Wang (Auteur), Wenshuo Gao (Auteur), Yihui Song (Auteur), Bin Yu (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2022-12-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The design of new ligands with high affinity and specificity against the targets of interest has been a central focus in drug discovery. As one of the most commonly used methods in drug discovery, the cyclization represents a feasible strategy to identify new lead compounds by increasing structural...