Calebin A: Analytical Development for Pharmacokinetics Study, Elucidation of Pharmacological Activities and Content Analysis of Natural Health Products

• Main Authors: Ana Luísa de P. Oliveira (Author), Stephanie E. Martinez (Author), Kalyanam Nagabushnam (Author), Muhammed Majeed (Author), Samaa Alrushaid (Author), Casey L. Sayre (Author), Neal M. Davies (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: To develop a bioanalytical assay using RP-HPLC to quantify the curcuminoid calebin A, to characterize its pharmacokinetics in rats after intravenous (IV) and oral (PO) administration, to identify its pharmacological activities and to evaluate its content in natural health products. Methods:...