Menin Coordinates C/EBPβ-Mediated TGF-β Signaling for Epithelial-Mesenchymal Transition and Growth Inhibition in Pancreatic Cancer

• Main Authors: Peng Cheng (Author), Ying Chen (Author), Tian-lin He (Author), Chao Wang (Author), Shi-wei Guo (Author), Hao Hu (Author), Chen-ming Ni (Author), Gang Jin (Author), Yi-jie Zhang (Author)
• Format: Book
• Published: Elsevier, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Menin displays either tumor suppression or promotion functions in a context-dependent manner. Previously, we proposed that Menin acts as a tumor suppressor by inhibiting cell growth in pancreatic ductal adenocarcinoma (PDAC), whereas the relationship between the Menin expression and overall survival...