Trichostatin A relieves anxiety-and depression-like symptoms in APP/PS1 mice

• Main Authors: Qiang Su (Author), Yu-Hua Ren (Author), Guo-Wei Liu (Author), Yan-Ping Gao (Author), Jiu-Xuan Zhang (Author), Jin-Nan Zhang (Author), Xia-Xia Pei (Author), Tian Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background:Cognitive deficits and behavioral disorders such as anxiety and depression are common manifestations of Alzheimer's disease (AD). Our previous work demonstrated that Trichostatin A (TSA) could alleviate neuroinflammatory plaques and improve cognitive disorders. AD, anxiety, and depre...