MicroRNA profiling of human primary macrophages exposed to dengue virus identifies miRNA-3614-5p as antiviral and regulator of ADAR1 expression.

• Main Authors: Mayra Diosa-Toro (Author), Liliana Echavarría-Consuegra (Author), Jacky Flipse (Author), Geysson Javier Fernández (Author), Joost Kluiver (Author), Anke van den Berg (Author), Silvio Urcuqui-Inchima (Author), Jolanda M Smit (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Due to the high burden of dengue disease worldwide, a better understanding of the interactions between dengue virus (DENV) and its human host cells is of the utmost importance. Although microRNAs modulate the outcome of several viral infections, their contribution to DENV replication is p...