MicroRNA profiling of human primary macrophages exposed to dengue virus identifies miRNA-3614-5p as antiviral and regulator of ADAR1 expression.

• Những tác giả chính: Mayra Diosa-Toro (Tác giả), Liliana Echavarría-Consuegra (Tác giả), Jacky Flipse (Tác giả), Geysson Javier Fernández (Tác giả), Joost Kluiver (Tác giả), Anke van den Berg (Tác giả), Silvio Urcuqui-Inchima (Tác giả), Jolanda M Smit (Tác giả)
• Định dạng: Sách
• Được phát hành: Public Library of Science (PLoS), 2017-10-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

BACKGROUND:Due to the high burden of dengue disease worldwide, a better understanding of the interactions between dengue virus (DENV) and its human host cells is of the utmost importance. Although microRNAs modulate the outcome of several viral infections, their contribution to DENV replication is p...