Human beta-defensin 3 is up-regulated in cutaneous leprosy type 1 reactions.

• Hauptverfasser: Anna L Cogen (Verfasst von), Stephen L Walker (Verfasst von), Chrissy H Roberts (Verfasst von), Deanna A Hagge (Verfasst von), Kapil D Neupane (Verfasst von), Saraswoti Khadge (Verfasst von), Diana N J Lockwood (Verfasst von)
• Format: Buch
• Veröffentlicht: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

BACKGROUND:Leprosy, a chronic granulomatous disease affecting the skin and nerves, is caused by Mycobacterium leprae (M. leprae). The type of leprosy developed depends upon the host immune response. Type 1 reactions (T1Rs), that complicate borderline and lepromatous leprosy, are due to an increase i...