Activation of Cryptic Antibiotic Biosynthetic Gene Clusters Guided by RNA-seq Data from Both <i>Streptomyces ansochromogenes</i> and ΔwblA

• Main Authors: Yue Li (Author), Haiying Yu (Author), Hanye Guan (Author), Jingjing Li (Author), Jihui Zhang (Author), Hua Xiang (Author), Jine Li (Author), Huarong Tan (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

With the increase of drug resistance caused by the improper use and abuse of antibiotics, human beings are facing a global health crisis. Sequencing of <i>Streptomyces</i> genomes revealed the presence of an important reservoir of secondary metabolic gene clusters for previously unsuspec...