Tolerability, Safety, Pharmacokinetics and Drug Interaction of Cefotaxime Sodium-Tazobactam Sodium Injection (6:1) Following Single and Multiple Intravenous Doses in Chinese Healthy Subjects

• Main Authors: Ning Chen (Author), Lu-Ning Sun (Author), Wen-Hui Hu (Author), Yi-Ya Wang (Author), Li-Jun Xie (Author), Juan Cheng (Author), Hong-Wen Zhang (Author), Yun Liu (Author), Yong-Qing Wang (Author), Li Ding (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

PurposeTo evaluate the tolerability, safety, pharmacokinetics and drug interaction of cefotaxime sodium-tazobactam sodium injection (6:1) in Chinese healthy subjects. The results of the safety and pharmacokinetic studies supported further clinical trials.MethodA randomized, single-blind, ascending d...