Co-amorphous solid dispersion systems of lacidipine-spironolactone with improved dissolution rate and enhanced physical stability

Co-amorphous solid dispersion systems of lacidipine-spironolactone with improved dissolution rate and enhanced physical stability

Co-amorphous solid dispersion (C-ASD) systems have attracted great attention to improve the solubility of poorly soluble drugs, but the selection of an appropriate stabilizer to stabilize amorphous forms is still a huge challenge. Herein, C-ASD system of two clinical combined used drugs (lacidipine...

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Main Authors: Zhaomeng Wang (Author), Mengchi Sun (Author), Tian Liu (Author), Zisen Gao (Author), Qing Ye (Author), Xiao Tan (Author), Yanxian Hou (Author), Jin Sun (Author), Dun Wang (Author), Zhonggui He (Author)
Format: Book
Published: Elsevier, 2019-01-01T00:00:00Z.
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