Identification of CD73 as the Antigen of an Antigen-Unknown Monoclonal Antibody Established by Exosome Immunization, and Its Antibody-Drug Conjugate Exerts an Antitumor Effect on Glioblastoma Cell Lines

• Главные авторы: Takahiro Anzai (Автор), Shinji Saijou (Автор), Hiroki Takashima (Автор), Misato Hara (Автор), Shingo Hanaoka (Автор), Yasuhiro Matsumura (Автор), Masahiro Yasunaga (Автор)
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• Опубликовано: MDPI AG, 2022-07-01T00:00:00Z.
• Предметы: article
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Development of antibodies against the native structure of membrane proteins with multiple transmembrane domains is challenging because it is difficult to prepare antigens with native structures. Previously, we successfully developed a monoclonal antibody against multi-pass membrane protein TMEM180 b...