Case Report: Two Cases of Pediatric Thrombotic Thrombocytopenic Purpura Treated With Combined Therapy

• Main Authors: Costanza Tripiciano (Author), Paola Zangari (Author), Mauro Montanari (Author), Giovanna Leone (Author), Laura Massella (Author), Lucia Garaboldi (Author), Michela Massoud (Author), Stefano Lancellotti (Author), Luisa Strocchio (Author), Emma Concetta Manno (Author), Paolo Palma (Author), Tiziana Corsetti (Author), Matteo Luciani (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy caused by a severely reduced activity of the von Willebrand factor-cleaving protease ADAMTS13. Over 95% of TTPs are acquired, due to autoantibody inhibitors. In children, acquired TTP is a very rare, life-threatening disease....