Aerosolizable Lipid Nanoparticles for Pulmonary Delivery of mRNA through Design of Experiments

• Váldodahkkit: Hairui Zhang (Dahkki), Jasmim Leal (Dahkki), Melissa R. Soto (Dahkki), Hugh D. C. Smyth (Dahkki), Debadyuti Ghosh (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2020-10-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Messenger RNA is a class of promising nucleic acid therapeutics to treat a variety of diseases, including genetic diseases. The development of a stable and efficacious mRNA pulmonary delivery system would enable high therapeutic concentrations locally in the lungs to improve efficacy and limit poten...