Aerosolizable Lipid Nanoparticles for Pulmonary Delivery of mRNA through Design of Experiments

• मुख्य लेखकों: Hairui Zhang (लेखक), Jasmim Leal (लेखक), Melissa R. Soto (लेखक), Hugh D. C. Smyth (लेखक), Debadyuti Ghosh (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2020-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Messenger RNA is a class of promising nucleic acid therapeutics to treat a variety of diseases, including genetic diseases. The development of a stable and efficacious mRNA pulmonary delivery system would enable high therapeutic concentrations locally in the lungs to improve efficacy and limit poten...