Ketone- and Cyano-Selenoesters to Overcome Efflux Pump, Quorum-Sensing, and Biofilm-Mediated Resistance

• Main Authors: Nikoletta Szemerédi (Author), Annamária Kincses (Author), Katerina Rehorova (Author), Lan Hoang (Author), Noemi Salardón-Jiménez (Author), Clotilde Sevilla-Hernández (Author), Jitka Viktorová (Author), Enrique Domínguez-Álvarez (Author), Gabriella Spengler (Author)
• Format: Book
• Published: MDPI AG, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The emergence of drug-resistant pathogens leads to a gradual decline in the efficacy of many antibacterial agents, which poses a serious problem for proper therapy. Multidrug resistance (MDR) mechanisms allow resistant bacteria to have limited uptake of drugs, modification of their target molecules,...